
NO, the signal to better life
The binding results in a cellular effect, which manifests as any number of changes in that cell. Molecules that are referred to as signaling molecules include proteins, peptides, amino acids, nucleotides, steroids, retinoids, fatty acids derivatives, and even dissolved gases such as nitric oxide and carbon monoxide. Why is NO called the most important signaling molecule? Because it acts inside and outside the cell as messenger, NO mediates diverse signaling pathways in target cells and is known to play an important role in many physiological or body processes including neuronal (brain) signaling; immune response (capacity to ward off infection or protect against autoimmune illnesses, such as lupus, etc,); inflammatory response (inflammation, even when silent, is the root cause of many if not all diseases); modulation of ion channels (ions required in production of electrical impulses that enables muscles to contract, including heart muscles); phagocytic defense mechanisms (capacity to immobilize and digest harmful bacteria, fungi, and viruses); sexual arousal in both males and females, and cardiovascular homeostasis or balance. The production of NO through this pathway takes into consideration the following steps- green leafy vegetables and/or fruits like beets, pomegranates, noni fruits, etc are chewed in the mouth and as admixing is achieved, the salivary bacteria produce enzymes that split the nitrate molecules to nitrites.








